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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732370
Species: Homo sapiens
RGD Object: Gene
Symbol: ARRB1
Name: arrestin beta 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ARRB1decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of ARRB1 genePMID:31601247
ARRB1increases expressionEXP 6480464CTDbisphenol A results in increased expression of ARRB1 mRNA; bisphenol A results in increased expression of ARRB1 proteinPMID:27685785 PMID:34186270
ARRB1affects methylationISOArrb1 (Mus musculus)6480464CTDbisphenol A affects the methylation of ARRB1 promoterPMID:27334623
ARRB1decreases expressionISOArrb1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ARRB1 mRNAPMID:24066056 PMID:25181051 PMID:34947998
ARRB1increases expressionISOArrb1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ARRB1 mRNAPMID:32145629
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