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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732313
Species: Mus musculus
RGD Object: Gene
Symbol: Insl3
Name: insulin-like 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Insl3decreases expressionISOInsl3 (Rattus norvegicus)6480464CTDbisphenol A analog results in decreased expression of INSL3 mRNA; bisphenol A analog results in decreased expression of INSL3 protein; bisphenol A results in decreased expression of INSL3 mRNA; bisphenol A results in decreased expression of INSL3 proteinPMID:30557795 PMID:35427877
Insl3decreases expressionISOINSL3 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of INSL3 mRNAPMID:23284716
Insl3increases expressionISOInsl3 (Rattus norvegicus)6480464CTDbisphenol A analog results in increased expression of INSL3 mRNAPMID:36214340
Insl3increases expressionISOINSL3 (Homo sapiens)6480464CTDbisphenol A results in increased expression of INSL3 proteinPMID:28482050
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