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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731981
Species: Homo sapiens
RGD Object: Gene
Symbol: KCNMA1
Name: potassium calcium-activated channel subfamily M alpha 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KCNMA1decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of KCNMA1 genePMID:31601247
KCNMA1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of KCNMA1 genePMID:31601247
KCNMA1decreases expressionISOKcnma1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of KCNMA1 mRNAPMID:25181051 PMID:30816183
KCNMA1decreases expressionISOKcnma1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of KCNMA1 mRNAPMID:31250031 PMID:32156529
KCNMA1increases methylationISOKcnma1 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of KCNMA1 genePMID:28505145
KCNMA1multiple interactionsISOKcnma1 (Mus musculus)6480464CTDESR2 protein affects the reaction [bisphenol A results in decreased expression of KCNMA1 mRNA]PMID:31250031
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