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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731621
Species: Homo sapiens
RGD Object: Gene
Symbol: VCP
Name: valosin containing protein
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VCPdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of VCP proteinPMID:34186270
VCPdecreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of VCP promoterPMID:30352284
VCPincreases expressionEXP 6480464CTDbisphenol A results in increased expression of VCP proteinPMID:33670352
VCPdecreases expressionISOVcp (Mus musculus)6480464CTDbisphenol A results in decreased expression of VCP proteinPMID:35999755
VCPincreases expressionISOVcp (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of VCP mRNA; bisphenol A results in increased expression of VCP proteinPMID:25181051 PMID:32145629
VCPincreases expressionISOVcp (Mus musculus)6480464CTDbisphenol A results in increased expression of VCP mRNA; bisphenol A results in increased expression of VCP proteinPMID:21932408 PMID:28279065
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