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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731380
Species: Homo sapiens
RGD Object: Gene
Symbol: AIFM1
Name: apoptosis inducing factor mitochondria associated 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AIFM1affects expressionEXP 6480464CTDbisphenol A affects the expression of AIFM1 mRNAPMID:21826169
AIFM1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of AIFM1 proteinPMID:34186270
AIFM1decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of AIFM1 genePMID:31601247
AIFM1increases expressionEXP 6480464CTDbisphenol A results in increased expression of AIFM1 proteinPMID:37567409
AIFM1multiple interactionsEXP 6480464CTD[[ginger extract results in increased abundance of Oils, Volatile] which co-treated with bisphenol A] affects the expression of AIFM1 proteinPMID:33376534
AIFM1affects localizationISOAifm1 (Rattus norvegicus)6480464CTDbisphenol A affects the localization of AIFM1 proteinPMID:25461564 PMID:27189055
AIFM1decreases expressionISOAifm1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of AIFM1 mRNAPMID:30816183 PMID:32528016 PMID:34947998
AIFM1increases expressionISOAifm1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of AIFM1 mRNAPMID:25181051 PMID:25461564
AIFM1multiple interactionsISOAifm1 (Rattus norvegicus)6480464CTDAcetylcysteine inhibits the reaction [bisphenol A affects the localization of AIFM1 protein]PMID:27189055
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