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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731311
Species: Homo sapiens
RGD Object: Gene
Symbol: GRM4
Name: glutamate metabotropic receptor 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GRM4affects methylationEXP 6480464CTDbisphenol A affects the methylation of GRM4 genePMID:31601247
GRM4affects expressionISOGrm4 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of GRM4 mRNAPMID:25181051
GRM4decreases expressionISOGrm4 (Mus musculus)6480464CTDbisphenol A results in decreased expression of GRM4 mRNAPMID:30951980
GRM4decreases expressionISOGrm4 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of GRM4 mRNAPMID:30816183 PMID:33441873
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