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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731296
Species: Homo sapiens
RGD Object: Gene
Symbol: HPRT1
Name: hypoxanthine phosphoribosyltransferase 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HPRT1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of HPRT1 mRNAPMID:29275510 PMID:33670352
HPRT1affects expressionISOHprt1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of HPRT1 mRNAPMID:25181051
HPRT1decreases expressionISOHprt1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of HPRT1 mRNAPMID:34947998
HPRT1increases expressionISOHprt1 (Mus musculus)6480464CTDbisphenol A results in increased expression of HPRT1 mRNAPMID:25270620
HPRT1increases expressionISOHprt1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of HPRT1 proteinPMID:22649256
HPRT1multiple interactionsISOHprt1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of HPRT1 mRNA; [bisphenol A co-treated with Estradiol] results in decreased expression of HPRT1 mRNAPMID:26496021 PMID:36041667
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