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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731009
Species: Mus musculus
RGD Object: Gene
Symbol: Tacr1
Name: tachykinin receptor 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tacr1increases expressionEXP 6480464CTDbisphenol A results in increased expression of TACR1 mRNAPMID:30951980
Tacr1decreases expressionISOTacr1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of TACR1 mRNAPMID:25181051 PMID:30816183
Tacr1decreases methylationISOTACR1 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of TACR1 genePMID:31601247
Tacr1increases expressionISOTACR1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of TACR1 mRNAPMID:29275510
Tacr1increases methylationISOTacr1 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of TACR1 genePMID:28505145
Tacr1multiple interactionsISOTacr1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of TACR1 mRNA; [bisphenol A co-treated with Testosterone] results in increased expression of TACR1 mRNAPMID:26496021
Tacr1multiple interactionsISOTACR1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of TACR1 genePMID:31601247
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