GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HMOX1 | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of HMOX1 mRNA | PMID:30903817 | HMOX1 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of HMOX1 mRNA; bisphenol A results in decreased expression of HMOX1 protein | PMID:29964091 PMID:31675489 PMID:34664771 PMID:36232920 PMID:38006930 | HMOX1 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of HMOX1 mRNA; bisphenol A results in increased expression of HMOX1 protein | PMID:23360430 PMID:25047013 PMID:29214717 PMID:29275510 PMID:29960846 PMID:30953815 PMID:32023790 PMID:33841860 PMID:36206637 | HMOX1 | multiple interactions | EXP | | 6480464 | CTD | [ALB protein co-treated with bisphenol A] results in increased expression of HMOX1 mRNA; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of HMOX1 mRNA]; bisphenol A promotes the reaction [HMOX1 protein binds to HMOX1 protein] | PMID:23360430 PMID:28628672 PMID:32023790 PMID:33841860 | HMOX1 | decreases expression | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A analog results in decreased expression of HMOX1 mRNA; bisphenol A analog results in decreased expression of HMOX1 protein; bisphenol A results in decreased expression of HMOX1 mRNA; bisphenol A results in decreased expression of HMOX1 protein | PMID:31091348 PMID:32145629 PMID:34947998 PMID:35427877 PMID:35465754 PMID:35648353 PMID:38006930 | HMOX1 | increases expression | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of HMOX1 mRNA; bisphenol A results in increased expression of HMOX1 protein | PMID:33221593 PMID:34281243 | HMOX1 | increases expression | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of HMOX1 mRNA; bisphenol A results in increased expression of HMOX1 protein | PMID:25181051 PMID:27143994 PMID:36206637 | HMOX1 | increases methylation | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased methylation of HMOX1 gene | PMID:28505145 | HMOX1 | multiple interactions | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of HMOX1 mRNA | PMID:37364641 | HMOX1 | multiple interactions | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | [Resveratrol analog co-treated with bisphenol A] results in increased expression of HMOX1 protein; Fluvastatin inhibits the reaction [bisphenol A results in decreased expression of HMOX1 protein]; Fluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in decreased expression of HMOX1 protein]]; Luteolin inhibits the reaction [bisphenol A results in decreased expression of HMOX1 protein]; taxifolin inhibits the reaction [bisphenol A results in decreased expression of HMOX1 protein]; taxifolin promotes the reaction [Fluvastatin inhibits the reaction [bisphenol A results in decreased expression of HMOX1 protein]] | PMID:31091348 PMID:34067838 PMID:35465754 | | ||||||||||||||||||||||
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