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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730878
Species: Homo sapiens
RGD Object: Gene
Symbol: NPPA
Name: natriuretic peptide A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NPPAincreases expressionEXP 6480464CTDbisphenol A results in increased expression of NPPA mRNAPMID:31830493
NPPAdecreases expressionISONppa (Mus musculus)6480464CTDbisphenol A results in decreased expression of NPPA mRNAPMID:26063408
NPPAdecreases expressionISONppa (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of NPPA mRNAPMID:25181051 PMID:34947998
NPPAincreases expressionISONppa (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of NPPA mRNAPMID:37611474
NPPAincreases methylationISONppa (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of NPPA genePMID:28505145
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