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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730840
Species: Homo sapiens
RGD Object: Gene
Symbol: GRK3
Name: G protein-coupled receptor kinase 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GRK3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GRK3 mRNAPMID:22576693
GRK3increases methylationEXP 6480464CTDbisphenol A results in increased methylation of GRK3 genePMID:22576693 PMID:31601247
GRK3decreases expressionISOGrk3 (Mus musculus)6480464CTDbisphenol A results in decreased expression of GRK3 mRNAPMID:32156529
GRK3decreases methylationISOGrk3 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of GRK3 promoterPMID:27312807
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