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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71022
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itga7
Name: integrin subunit alpha 7
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itga7affects expressionEXP 6480464CTDbisphenol A affects the expression of ITGA7 mRNAPMID:25181051
Itga7increases methylationEXP 6480464CTDbisphenol A results in increased methylation of ITGA7 genePMID:28505145
Itga7multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of ITGA7 promoterPMID:23359474
Itga7decreases expressionISOITGA7 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of ITGA7 proteinPMID:34186270
Itga7decreases expressionISOItga7 (Mus musculus)6480464CTDbisphenol A results in decreased expression of ITGA7 mRNAPMID:37105096
Itga7increases expressionISOItga7 (Mus musculus)6480464CTDbisphenol A results in increased expression of ITGA7 mRNAPMID:32156529
Itga7increases methylationISOItga7 (Mus musculus)6480464CTDbisphenol A results in increased methylation of ITGA7 promoterPMID:27312807
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