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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70824
Species: Homo sapiens
RGD Object: Gene
Symbol: MET
Name: MET proto-oncogene, receptor tyrosine kinase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
METincreases expressionEXP 6480464CTDbisphenol A results in increased expression of MET mRNAPMID:19371625
METincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of MET genePMID:31601247
METaffects expressionISOMet (Rattus norvegicus)6480464CTDbisphenol A affects the expression of MET mRNAPMID:32145629
METdecreases expressionISOMet (Mus musculus)6480464CTDbisphenol A results in decreased expression of MET mRNAPMID:32365465
METdecreases expressionISOMet (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of MET mRNAPMID:25181051 PMID:30816183
METincreases expressionISOMet (Mus musculus)6480464CTDbisphenol A results in increased expression of MET mRNAPMID:30951980 PMID:32156529
METmultiple interactionsISOMet (Rattus norvegicus)6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MET mRNAPMID:25607892
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