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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70083
Species: Mus musculus
RGD Object: Gene
Symbol: Rgs4
Name: regulator of G-protein signaling 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rgs4decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of RGS4 mRNAPMID:37105096
Rgs4decreases expressionISORGS4 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of RGS4 mRNAPMID:29275510
Rgs4increases expressionISORgs4 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of RGS4 mRNAPMID:25181051 PMID:32145629
Rgs4increases methylationISORgs4 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of RGS4 genePMID:28505145
Rgs4multiple interactionsISORgs4 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of RGS4 mRNAPMID:36041667
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