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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69659
Species: Homo sapiens
RGD Object: Gene
Symbol: ICAM1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ICAM1affects expressionEXP 6480464CTDbisphenol A affects the expression of ICAM1 mRNAPMID:30903817
ICAM1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ICAM1 mRNA; bisphenol A results in decreased expression of ICAM1 proteinPMID:30352284 PMID:33953208
ICAM1decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of ICAM1 promoterPMID:33953208
ICAM1increases expressionEXP 6480464CTDbisphenol A results in increased expression of ICAM1 mRNA; bisphenol A results in increased expression of ICAM1 proteinPMID:25619500 PMID:33683587 PMID:35628159
ICAM1multiple interactionsEXP 6480464CTDbisphenol A inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]PMID:32559890
ICAM1affects expressionISOIcam1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of ICAM1 mRNAPMID:25181051
ICAM1decreases expressionISOIcam1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ICAM1 mRNAPMID:30816183 PMID:32528016 PMID:34947998
ICAM1increases expressionISOIcam1 (Mus musculus)6480464CTDbisphenol A results in increased expression of ICAM1 mRNAPMID:26063408
ICAM1increases methylationISOIcam1 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of ICAM1 genePMID:28505145
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