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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69454
Species: Mus musculus
RGD Object: Gene
Symbol: Lcn2
Name: lipocalin 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcn2affects expressionEXP 6480464CTDbisphenol A affects the expression of LCN2 mRNAPMID:27082013
Lcn2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of LCN2 mRNA; bisphenol A results in decreased expression of LCN2 proteinPMID:27312807 PMID:32926169 PMID:33221593
Lcn2increases expressionEXP 6480464CTDbisphenol A results in increased expression of LCN2 mRNAPMID:32156529 PMID:34281243
Lcn2multiple interactionsEXP 6480464CTD[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LCN2 mRNA]PMID:27082013
Lcn2affects expressionISOLcn2 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of LCN2 mRNAPMID:25181051
Lcn2decreases expressionISOLcn2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of LCN2 mRNAPMID:32145629 PMID:34947998
Lcn2decreases expressionISOLCN2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of LCN2 mRNAPMID:36232920
Lcn2increases expressionISOLcn2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of LCN2 mRNAPMID:15456929
Lcn2increases expressionISOLCN2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of LCN2 mRNAPMID:29718440
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