Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69114
Species: Mus musculus
RGD Object: Gene
Symbol: Pdk4
Name: pyruvate dehydrogenase kinase, isoenzyme 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdk4affects expressionEXP 6480464CTDbisphenol A affects the expression of PDK4 mRNAPMID:32926169
Pdk4increases expressionEXP 6480464CTDbisphenol A results in increased expression of PDK4 mRNAPMID:35341816
Pdk4affects expressionISOPdk4 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of PDK4 mRNAPMID:30903817 PMID:32145629
Pdk4affects expressionISOPDK4 (Homo sapiens)6480464CTDbisphenol A affects the expression of PDK4 mRNAPMID:20170705
Pdk4decreases expressionISOPdk4 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of PDK4 mRNAPMID:25181051 PMID:30816183
Pdk4decreases expressionISOPDK4 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PDK4 mRNAPMID:27685785
Pdk4increases expressionISOPDK4 (Homo sapiens)6480464CTDbisphenol A results in increased expression of PDK4 mRNAPMID:34627044
Pdk4multiple interactionsISOPDK4 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PDK4 mRNAPMID:28628672
Go Back to source page   Continue to Ontology report