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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68408
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lasp1
Name: LIM and SH3 protein 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lasp1affects expressionEXP 6480464CTDbisphenol A affects the expression of LASP1 mRNAPMID:25181051
Lasp1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of LASP1 mRNAPMID:30816183 PMID:34947998
Lasp1decreases expressionISOLASP1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of LASP1 proteinPMID:37664457
Lasp1decreases expressionISOLasp1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of LASP1 proteinPMID:35999755
Lasp1increases expressionISOLasp1 (Mus musculus)6480464CTDbisphenol A results in increased expression of LASP1 mRNAPMID:32156529
Lasp1multiple interactionsISOLASP1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of LASP1 genePMID:31601247
Lasp1multiple interactionsISOLasp1 (Mus musculus)6480464CTD[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of LASP1 proteinPMID:35999755
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