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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cacna2d2
Name: calcium voltage-gated channel auxiliary subunit alpha2delta 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CACNA2D2 mRNA

PMID:25181051
multiple interactionsEXP 6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA2D2 mRNA, [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA2D2 mRNA

PMID:25607892
decreases expressionISORGD:13322106480464CTDbisphenol A results in decreased expression of CACNA2D2 mRNA

PMID:25594700
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.