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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628828
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1d2
Name: nuclear receptor subfamily 1, group D, member 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1d2affects expressionEXP 6480464CTDbisphenol A affects the expression of NR1D2 mRNAPMID:32145629
Nr1d2increases expressionEXP 6480464CTDbisphenol A results in increased expression of NR1D2 mRNAPMID:30816183 PMID:35192832
Nr1d2affects methylationISONr1d2 (Mus musculus)6480464CTDbisphenol A affects the methylation of NR1D2 promoterPMID:27334623
Nr1d2increases expressionISONR1D2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of NR1D2 mRNAPMID:29275510
Nr1d2increases expressionISONr1d2 (Mus musculus)6480464CTDbisphenol A results in increased expression of NR1D2 mRNAPMID:25594700
Nr1d2multiple interactionsISONr1d2 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of NR1D2 mRNAPMID:28433925
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