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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621746
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gchfr
Name: GTP cyclohydrolase I feedback regulator
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gchfrdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GCHFR mRNAPMID:25181051 PMID:32145629 PMID:34947998
Gchfrincreases expressionEXP 6480464CTDbisphenol A results in increased expression of GCHFR mRNAPMID:30816183 PMID:32528016
Gchfraffects expressionISOGCHFR (Homo sapiens)6480464CTDbisphenol A affects the expression of GCHFR mRNAPMID:30903817
Gchfrincreases expressionISOGchfr (Mus musculus)6480464CTDbisphenol A results in increased expression of GCHFR mRNAPMID:32156529 PMID:33221593 PMID:38074096
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