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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621703
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxc2
Name: forkhead box C2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxc2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of FOXC2 mRNAPMID:30816183 PMID:32528016 PMID:34947998
Foxc2increases expressionEXP 6480464CTDbisphenol A results in increased expression of FOXC2 mRNAPMID:29323181
Foxc2affects methylationISOFoxc2 (Mus musculus)6480464CTDbisphenol A affects the methylation of FOXC2 promoterPMID:27334623
Foxc2increases expressionISOFoxc2 (Mus musculus)6480464CTDbisphenol A results in increased expression of FOXC2 mRNAPMID:30951980 PMID:32156529
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