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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621642
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tie1affects expressionEXP 6480464CTDbisphenol A affects the expression of TIE1 mRNAPMID:25181051
Tie1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TIE1 mRNAPMID:30816183 PMID:32528016 PMID:34947998
Tie1affects expressionISOTIE1 (Homo sapiens)6480464CTDbisphenol A affects the expression of TIE1 mRNAPMID:21826169
Tie1increases expressionISOTie1 (Mus musculus)6480464CTDbisphenol A results in increased expression of TIE1 mRNAPMID:30951980 PMID:32156529 PMID:33221593
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