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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621548
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zbtb18
Name: zinc finger and BTB domain containing 18
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zbtb18affects expressionEXP 6480464CTDbisphenol A affects the expression of ZBTB18 mRNAPMID:25181051
Zbtb18increases expressionEXP 6480464CTDbisphenol A results in increased expression of ZBTB18 mRNAPMID:32145629
Zbtb18increases methylationEXP 6480464CTDbisphenol A results in increased methylation of ZBTB18 genePMID:28505145
Zbtb18affects methylationISOZbtb18 (Mus musculus)6480464CTDbisphenol A affects the methylation of ZBTB18 promoterPMID:27334623
Zbtb18decreases methylationISOZbtb18 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of ZBTB18 promoterPMID:27312807
Zbtb18increases expressionISOZBTB18 (Homo sapiens)6480464CTDbisphenol A results in increased expression of ZBTB18 mRNAPMID:31715268
Zbtb18multiple interactionsISOZBTB18 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of ZBTB18 genePMID:31601247
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