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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62139
Species: Mus musculus
RGD Object: Gene
Symbol: Gpam
Name: glycerol-3-phosphate acyltransferase, mitochondrial
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpamincreases expressionEXP 6480464CTDbisphenol A results in increased expression of GPAM mRNAPMID:21932408 PMID:25594700 PMID:28483554 PMID:28796629
Gpamaffects expressionISOGPAM (Homo sapiens)6480464CTDbisphenol A affects the expression of GPAM mRNAPMID:30903817
Gpamdecreases expressionISOGpam (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of GPAM mRNAPMID:25181051
Gpamincreases expressionISOGPAM (Homo sapiens)6480464CTDbisphenol A results in increased expression of GPAM mRNAPMID:25619500 PMID:28483554
Gpamincreases expressionISOGpam (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of GPAM mRNA; bisphenol A results in increased expression of GPAM proteinPMID:30816183 PMID:32145629 PMID:32528016 PMID:34947998
Gpammultiple interactionsISOGPAM (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of GPAM gene; MIR192 mRNA inhibits the reaction [bisphenol A results in increased expression of GPAM mRNA]PMID:28483554 PMID:31601247
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