GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Acaca | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of ACACA mRNA | PMID:25181051 | Acaca | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of ACACA mRNA | PMID:28657538 PMID:32145629 | Acaca | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of ACACA mRNA | PMID:20019905 PMID:24988533 PMID:29097150 PMID:31551937 PMID:31661889 PMID:31771501 PMID:32339907 PMID:34165232 PMID:34947998 PMID:36137816 | Acaca | increases methylation | EXP | | 6480464 | CTD | bisphenol A results in increased methylation of ACACA gene | PMID:28505145 | Acaca | multiple interactions | EXP | | 6480464 | CTD | bisphenol A promotes the reaction [Fructose results in increased expression of ACACA mRNA]; Fructose promotes the reaction [bisphenol A results in increased expression of ACACA mRNA]; lithospermate B inhibits the reaction [bisphenol A results in increased expression of ACACA mRNA] | PMID:31661889 PMID:34165232 | Acaca | affects expression | ISO | Acaca (Mus musculus) | 6480464 | CTD | bisphenol A affects the expression of ACACA mRNA | PMID:32623698 | Acaca | decreases expression | ISO | Acaca (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of ACACA mRNA | PMID:27502578 | Acaca | decreases expression | ISO | ACACA (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of ACACA protein | PMID:37567409 | Acaca | increases expression | ISO | Acaca (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of ACACA mRNA; bisphenol A results in increased expression of ACACA protein | PMID:21932408 PMID:28796629 PMID:37105096 PMID:37701206 | Acaca | increases expression | ISO | ACACA (Homo sapiens) | 6480464 | CTD | bisphenol A analog results in increased expression of ACACA mRNA; bisphenol A results in increased expression of ACACA mRNA; bisphenol A results in increased expression of ACACA protein | PMID:25047013 PMID:27014939 PMID:29275510 PMID:32623698 PMID:32763284 PMID:34186270 | Acaca | multiple interactions | ISO | Acaca (Mus musculus) | 6480464 | CTD | [1-Methyl-3-isobutylxanthine co-treated with bisphenol A co-treated with INS protein] results in increased expression of ACACA protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ACACA mRNA; [bisphenol A results in increased susceptibility to sodium arsenite] which results in increased expression of ACACA mRNA; [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ACACA mRNA; [sodium arsenite results in increased susceptibility to bisphenol A] which results in increased expression of ACACA mRNA; bisphenol A results in increased expression of and results in increased phosphorylation of ACACA protein; Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACA mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACA protein] | PMID:26820058 PMID:28796629 PMID:30208560 PMID:30722647 PMID:35739755 PMID:37701206 | Acaca | multiple interactions | ISO | ACACA (Homo sapiens) | 6480464 | CTD | N-piperidinyl-(8-chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrobenzo(6,7)cyclohepta(1,2-c)pyrazole-3-carboxamide) inhibits the reaction [bisphenol A results in increased expression of ACACA mRNA] | PMID:27014939 | | ||||||||||||||||||||||
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