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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621215
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vsx2
Name: visual system homeobox 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vsx2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of VSX2 mRNAPMID:25181051 PMID:34947998
Vsx2increases expressionEXP 6480464CTDbisphenol A results in increased expression of VSX2 mRNAPMID:30816183 PMID:32528016
Vsx2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of VSX2 genePMID:28505145
Vsx2multiple interactionsEXP 6480464CTDbisphenol A inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of VSX2 mRNA]PMID:18653720
Vsx2decreases expressionISOVsx2 (Mus musculus)6480464CTDbisphenol A results in decreased expression of VSX2 mRNAPMID:35479511
Vsx2increases expressionISOVSX2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of VSX2 mRNAPMID:36126549
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