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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621053
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lamc2
Name: laminin subunit gamma 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lamc2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of LAMC2 mRNAPMID:30816183 PMID:32528016 PMID:34947998
Lamc2increases expressionEXP 6480464CTDbisphenol A results in increased expression of LAMC2 mRNAPMID:32145629
Lamc2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of LAMC2 mRNA; [bisphenol A co-treated with Testosterone] results in decreased expression of LAMC2 mRNAPMID:26496021
Lamc2decreases expressionISOLAMC2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of LAMC2 mRNAPMID:36232920
Lamc2increases expressionISOLamc2 (Mus musculus)6480464CTDbisphenol A results in increased expression of LAMC2 mRNAPMID:30951980 PMID:32156529
Lamc2multiple interactionsISOLAMC2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of LAMC2 gene; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of LAMC2 mRNAPMID:28628672 PMID:31601247
Lamc2multiple interactionsISOLamc2 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of LAMC2 mRNAPMID:30951980
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