GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lif | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of LIF mRNA | PMID:25181051 | Lif | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of LIF mRNA | PMID:30816183 PMID:32528016 | Lif | affects expression | ISO | LIF (Homo sapiens) | 6480464 | CTD | bisphenol A affects the expression of LIF mRNA | PMID:30903817 | Lif | decreases expression | ISO | LIF (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of LIF mRNA | PMID:27685785 PMID:31230753 | Lif | decreases expression | ISO | Lif (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of LIF mRNA | PMID:27022677 PMID:30061528 | Lif | increases expression | ISO | Lif (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of LIF mRNA | PMID:32156529 | Lif | multiple interactions | ISO | LIF (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]; [bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]; [bisphenol A co-treated with LIF protein] results in increased phosphorylation of MAPK1 protein; [bisphenol A co-treated with LIF protein] results in increased phosphorylation of MAPK3 protein; bisphenol A promotes the reaction [LIF protein results in increased activity of STAT3 protein]; Tamoxifen inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] | PMID:14975756 | Lif | multiple interactions | ISO | Lif (Mus musculus) | 6480464 | CTD | [bisphenol A co-treated with LIF protein] affects the expression of EIF3J1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of ABCA1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of AHNAK mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of APOB mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of AQP3 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of BIRC6 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of CUBN mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of DNAH8 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of DST mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of DYNC1H1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of EPPK1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of FAT1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of GRK4 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of H2-Q9 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of HECTD4 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of HIST1H2AF mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of HIST2H2AA2 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of HSPG2 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of KMT2A mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of KMT2D mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of LAMA1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of LRP1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of LRP2 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of MACF1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of MDN1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of MED12L mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of NBEAL1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of NDUFA4L2 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of NFAT5 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of PRR19 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of RPLP2-PS1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of TWIST1 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of UBR4 mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of VWF mRNA; [bisphenol A co-treated with LIF protein] results in decreased expression of ZBED6 mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of DUXBL1 mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of FTHL17-PS1 mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of H2AC13 mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of H2AC18 mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of PBLD1 mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of PLA2G4B mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of PPP1R2-PS3 mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of RNASET2B mRNA; [bisphenol A co-treated with LIF protein] results in increased expression of TMEM254 mRNA | PMID:30951980 | | ||||||||||||||||||||||
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