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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620850
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nppc
Name: natriuretic peptide C
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nppcdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of NPPC mRNAPMID:15518916 PMID:25181051
Nppcincreases expressionISONPPC (Homo sapiens)6480464CTDbisphenol A results in increased expression of NPPC mRNAPMID:31230753 PMID:34831106
Nppcmultiple interactionsISONPPC (Homo sapiens)6480464CTDFulvestrant inhibits the reaction [bisphenol A results in increased expression of NPPC mRNA]PMID:34831106
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