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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620773
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apom
Name: apolipoprotein M
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apomincreases expressionEXP 6480464CTDbisphenol A results in increased expression of APOM mRNAPMID:34947998
Apomaffects expressionISOAPOM (Homo sapiens)6480464CTDbisphenol A affects the expression of APOM mRNAPMID:30903817
Apomincreases expressionISOAPOM (Homo sapiens)6480464CTDbisphenol A results in increased expression of APOM proteinPMID:33376534
Apomincreases expressionISOApom (Mus musculus)6480464CTDbisphenol A results in increased expression of APOM mRNAPMID:30245210 PMID:33221593 PMID:34585602
Apommultiple interactionsISOAPOM (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of APOM gene; [ginger extract results in increased abundance of Oils, Volatile] inhibits the reaction [bisphenol A results in increased expression of APOM protein]PMID:31601247 PMID:33376534
Apommultiple interactionsISOApom (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of APOM mRNAPMID:28433925
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