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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620728
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnmb4
Name: potassium calcium-activated channel subfamily M regulatory beta subunit 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnmb4decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of KCNMB4 mRNAPMID:25181051
Kcnmb4increases methylationEXP 6480464CTDbisphenol A results in increased methylation of KCNMB4 genePMID:28505145
Kcnmb4multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Genistein] results in increased methylation of KCNMB4 genePMID:28505145
Kcnmb4increases methylationISOKcnmb4 (Mus musculus)6480464CTDbisphenol A results in increased methylation of KCNMB4 promoterPMID:27312807
Kcnmb4multiple interactionsISOKCNMB4 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of KCNMB4 genePMID:31601247
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