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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620721
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Blvra
Name: biliverdin reductase A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Blvraincreases expressionEXP 6480464CTDbisphenol A results in increased expression of BLVRA mRNAPMID:25181051
Blvradecreases expressionISOBLVRA (Homo sapiens)6480464CTDbisphenol A results in decreased expression of BLVRA proteinPMID:31675489
Blvraincreases expressionISOBLVRA (Homo sapiens)6480464CTDbisphenol A results in increased expression of BLVRA proteinPMID:34186270 PMID:37567409
Blvraincreases methylationISOBLVRA (Homo sapiens)6480464CTDbisphenol A results in increased methylation of BLVRA genePMID:31601247
Blvraincreases methylationISOBlvra (Mus musculus)6480464CTDbisphenol A results in increased methylation of BLVRA promoterPMID:27312807
Blvramultiple interactionsISOBLVRA (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of BLVRA genePMID:31601247
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