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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620717
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l2
Name: Bcl2-like 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of BCL2L2 mRNAPMID:30816183 PMID:32145629 PMID:32528016 PMID:34947998
Bcl2l2increases expressionEXP 6480464CTDbisphenol A results in increased expression of BCL2L2 mRNAPMID:25181051
Bcl2l2affects expressionISOBCL2L2 (Homo sapiens)6480464CTDbisphenol A affects the expression of BCL2L2 mRNAPMID:30903817
Bcl2l2decreases expressionISOBCL2L2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of BCL2L2 mRNA; bisphenol A results in decreased expression of BCL2L2 proteinPMID:21277958 PMID:29275510
Bcl2l2increases expressionISOBCL2L2 (Homo sapiens)6480464CTDbisphenol A analog results in increased expression of BCL2L2 mRNAPMID:32387340
Bcl2l2multiple interactionsISOBCL2L2 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of BCL2L2 mRNAPMID:28628672
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