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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620479
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cand1
Name: cullin-associated and neddylation-dissociated 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cand1increases expressionEXP 6480464CTDbisphenol A results in increased expression of CAND1 mRNAPMID:25181051 PMID:29097150
Cand1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of CAND1 mRNAPMID:26496021
Cand1decreases expressionISOCAND1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CAND1 proteinPMID:33376534
Cand1decreases methylationISOCand1 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of CAND1 promoterPMID:27312807
Cand1increases expressionISOCAND1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of CAND1 proteinPMID:34186270
Cand1increases methylationISOCand1 (Mus musculus)6480464CTDbisphenol A results in increased methylation of CAND1 promoterPMID:27312807
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