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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620474
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sox9
Name: SRY-box transcription factor 9
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sox9decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SOX9 mRNA; bisphenol A results in decreased expression of SOX9 proteinPMID:34973380
Sox9increases expressionEXP 6480464CTDbisphenol A results in increased expression of SOX9 mRNAPMID:34947998
Sox9affects expressionISOSOX9 (Homo sapiens)6480464CTDbisphenol A affects the expression of SOX9 mRNAPMID:30903817
Sox9affects methylationISOSox9 (Mus musculus)6480464CTDbisphenol A affects the methylation of SOX9 promoterPMID:27334623
Sox9decreases expressionISOSox9 (Mus musculus)6480464CTDbisphenol A results in decreased expression of SOX9 mRNAPMID:22732146
Sox9increases expressionISOSOX9 (Homo sapiens)6480464CTDbisphenol A results in increased expression of SOX9 mRNAPMID:29718440
Sox9increases expressionISOSox9 (Mus musculus)6480464CTDbisphenol A results in increased expression of SOX9 mRNAPMID:32156529
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