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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61964
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gstm5
Name: glutathione S-transferase, mu 5
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstm5affects expressionEXP 6480464CTDbisphenol A affects the expression of GSTM3 mRNAPMID:25181051
Gstm5increases expressionISOGSTM3 (Homo sapiens)6480464CTDbisphenol A results in increased expression of GSTM3 proteinPMID:37567409
Gstm5increases expressionISOGstm5 (Mus musculus)6480464CTDbisphenol A results in increased expression of GSTM3 mRNAPMID:33221593
Gstm5multiple interactionsISOGstm5 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM3 mRNAPMID:28433925
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