Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3907
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Clu
Name: clusterin
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cluaffects expressionEXP 6480464CTDbisphenol A affects the expression of CLU mRNAPMID:30903817
Cludecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CLU mRNAPMID:30816183 PMID:32145629
Cluincreases expressionEXP 6480464CTDbisphenol A results in increased expression of CLU mRNA; bisphenol A results in increased expression of CLU proteinPMID:21536718 PMID:25181051
Clumultiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CLU mRNA; bisphenol A inhibits the reaction [Ethinyl Estradiol results in decreased expression of CLU mRNA]PMID:16639590 PMID:36041667
Cluaffects expressionISOCLU (Homo sapiens)6480464CTDbisphenol A affects the expression of CLU mRNAPMID:30903817 PMID:36466761
Cluincreases expressionISOCLU (Homo sapiens)6480464CTDbisphenol A results in increased expression of CLU mRNAPMID:29275510
Cluincreases expressionISOClu (Mus musculus)6480464CTDbisphenol A results in increased expression of CLU mRNAPMID:30951980 PMID:34585602
Clumultiple interactionsISOCLU (Homo sapiens)6480464CTD4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [bisphenol A inhibits the reaction [Doxorubicin results in increased expression of CLU mRNA]]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A inhibits the reaction [Doxorubicin results in increased expression of CLU mRNA]]; bisphenol A inhibits the reaction [Doxorubicin results in increased expression of CLU mRNA]; fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [Doxorubicin results in increased expression of CLU mRNA]]PMID:26320837
Clumultiple interactionsISOClu (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of CLU mRNAPMID:30951980
Go Back to source page   Continue to Ontology report