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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3845
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tf
Name: transferrin
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tfaffects expressionEXP 6480464CTDbisphenol A affects the expression of TF mRNAPMID:30903817
Tfdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TF mRNA; bisphenol A results in decreased expression of TF protein; bisphenol A results in decreased expression of TRF proteinPMID:21574817 PMID:31369804 PMID:34947998
Tfincreases expressionEXP 6480464CTDbisphenol A results in increased expression of TF mRNA; bisphenol A results in increased expression of TF proteinPMID:25181051 PMID:30816183 PMID:32145629
Tfincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of TF genePMID:28505145
Tfmultiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in decreased expression of TF protein]; [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of TF mRNAPMID:21574817 PMID:36041667
Tfaffects expressionISOTF (Homo sapiens)6480464CTDbisphenol A affects the expression of TF mRNAPMID:30903817
Tfdecreases expressionISOTrf (Mus musculus)6480464CTDbisphenol A results in decreased expression of TRF mRNAPMID:30951980
Tfdecreases expressionISOTF (Homo sapiens)6480464CTDbisphenol A results in decreased expression of TF proteinPMID:33376534 PMID:34186270
Tfincreases expressionISOTrf (Mus musculus)6480464CTDbisphenol A results in increased expression of TRF mRNAPMID:30245210 PMID:33221593
Tfincreases expressionISOTF (Homo sapiens)6480464CTDbisphenol A results in increased expression of TF proteinPMID:37567409 PMID:37664457
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