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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3829
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tcf12
Name: transcription factor 12
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tcf12affects expressionEXP 6480464CTDbisphenol A affects the expression of TCF12 mRNAPMID:25181051
Tcf12decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TCF12 mRNAPMID:34947998
Tcf12increases expressionEXP 6480464CTDbisphenol A results in increased expression of TCF12 mRNAPMID:30816183
Tcf12affects methylationISOTcf12 (Mus musculus)6480464CTDbisphenol A affects the methylation of TCF12 promoterPMID:27334623
Tcf12decreases methylationISOTCF12 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of TCF12 genePMID:31601247
Tcf12multiple interactionsISOTCF12 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of TCF12 genePMID:31601247
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