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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3477
Species: Rattus norvegicus
RGD Object: Gene
Symbol: RT1-DOa
Name: RT1 class II, locus DOa
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RT1-DOadecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of HLA-DOA mRNAPMID:25181051
RT1-DOamultiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of RT1-DOA mRNAPMID:36041667
RT1-DOaincreases methylationISOHLA-DOA (Homo sapiens)6480464CTDbisphenol A results in increased methylation of HLA-DOA genePMID:31601247
RT1-DOamultiple interactionsISOHLA-DOA (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of HLA-DOA genePMID:31601247
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