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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2948
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aadat
Name: aminoadipate aminotransferase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aadatdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of AADAT mRNAPMID:25181051 PMID:32145629
Aadatincreases expressionEXP 6480464CTDbisphenol A results in increased expression of AADAT mRNAPMID:30816183 PMID:32528016
Aadatincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of AADAT genePMID:28505145
Aadatmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of AADAT mRNA; [bisphenol A co-treated with Testosterone] results in increased expression of AADAT mRNAPMID:26496021
Aadatdecreases expressionISOAadat (Mus musculus)6480464CTDbisphenol A results in decreased expression of AADAT mRNAPMID:33221593
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