GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il5 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of IL5 mRNA | PMID:25181051 | Il5 | decreases methylation | ISO | IL5 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased methylation of IL5 gene | PMID:31601247 | Il5 | increases expression | ISO | Il5 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of IL5 mRNA; bisphenol A results in increased expression of IL5 protein | PMID:29161229 PMID:29737898 PMID:31788436 | Il5 | multiple interactions | ISO | Il5 (Mus musculus) | 6480464 | CTD | [bisphenol A affects the susceptibility to Ovalbumin] which results in increased expression of IL5 protein; [bisphenol A results in increased susceptibility to Ovalbumin] which results in increased expression of IL5 mRNA; [Ovalbumin co-treated with bisphenol A] results in increased expression of and results in increased secretion of IL5 protein; [Ovalbumin co-treated with bisphenol A] results in increased secretion of IL5 protein; bisphenol A inhibits the reaction [1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone inhibits the reaction [Ovalbumin results in increased expression of IL5 protein]]; bisphenol A promotes the reaction [OVAL protein results in increased secretion of IL5 protein]; bisphenol A promotes the reaction [Ovalbumin results in increased expression of IL5 mRNA]; bisphenol A promotes the reaction [Ovalbumin results in increased expression of IL5 protein] | PMID:27087817 PMID:29737898 PMID:31788436 PMID:32012983 PMID:35533451 | | ||||||||||||||||||||||
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