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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2895
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il2ra
Name: interleukin 2 receptor subunit alpha
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il2radecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of IL2RA mRNAPMID:25181051
Il2ramultiple interactionsEXP 6480464CTDbisphenol A affects the reaction [Antigen-Antibody Complex results in increased expression of IL2RA protein]PMID:29427786
Il2radecreases expressionISOIl2ra (Mus musculus)6480464CTDbisphenol A results in decreased expression of IL2RA mRNAPMID:32156529
Il2radecreases methylationISOIL2RA (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of IL2RA genePMID:31601247
Il2raincreases expressionISOIL2RA (Homo sapiens)6480464CTDbisphenol A results in increased expression of IL2RA proteinPMID:29066408
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