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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2323959
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Auts2
Name: activator of transcription and developmental regulator AUTS2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Auts2affects expressionEXP 6480464CTDbisphenol A affects the expression of AUTS2 mRNAPMID:25181051
Auts2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of AUTS2 mRNAPMID:30816183
Auts2increases expressionEXP 6480464CTDbisphenol A results in increased expression of AUTS2 mRNAPMID:34947998
Auts2affects methylationISOAUTS2 (Homo sapiens)6480464CTDbisphenol A affects the methylation of AUTS2 genePMID:31601247
Auts2decreases expressionISOAUTS2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of AUTS2 mRNAPMID:33670352
Auts2decreases methylationISOAuts2 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of AUTS2 promoterPMID:27312807
Auts2increases expressionISOAuts2 (Mus musculus)6480464CTDbisphenol A results in increased expression of AUTS2 mRNAPMID:26063408
Auts2multiple interactionsISOAUTS2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of AUTS2 genePMID:31601247
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