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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1618804
Species: Mus musculus
RGD Object: Gene
Symbol: Itpkb
Name: inositol 1,4,5-trisphosphate 3-kinase B
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itpkbdecreases expressionISOItpkb (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ITPKB mRNAPMID:25181051 PMID:32145629
Itpkbdecreases methylationISOITPKB (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of ITPKB genePMID:31601247
Itpkbincreases expressionISOITPKB (Homo sapiens)6480464CTDbisphenol A results in increased expression of ITPKB mRNAPMID:27685785
Itpkbincreases expressionISOItpkb (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ITPKB mRNAPMID:29097150 PMID:30816183 PMID:32528016 PMID:34947998
Itpkbmultiple interactionsISOItpkb (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Testosterone] results in decreased expression of ITPKB mRNAPMID:26496021
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