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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1618392
Species: Mus musculus
RGD Object: Gene
Symbol: Pnkd
Name: paroxysmal nonkinesiogenic dyskinesia
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pnkddecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PNKD mRNAPMID:32926169
Pnkdincreases expressionEXP 6480464CTDbisphenol A results in increased expression of PNKD mRNAPMID:33221593
Pnkdaffects expressionISOPnkd (Rattus norvegicus)6480464CTDbisphenol A affects the expression of PNKD mRNAPMID:25181051 PMID:30903817
Pnkddecreases methylationISOPNKD (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of PNKD genePMID:31601247
Pnkddecreases methylationISOPnkd (Rattus norvegicus)6480464CTDbisphenol A results in decreased methylation of PNKD genePMID:28505145
Pnkdmultiple interactionsISOPNKD (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of PNKD genePMID:31601247
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