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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1617975
Species: Mus musculus
RGD Object: Gene
Symbol: Fat4
Name: FAT atypical cadherin 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fat4decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of FAT4 mRNAPMID:26063408 PMID:35341816
Fat4increases expressionEXP 6480464CTDbisphenol A results in increased expression of FAT4 mRNAPMID:35598803
Fat4decreases expressionISOFAT4 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of FAT4 proteinPMID:31675489
Fat4decreases expressionISOFat4 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of FAT4 mRNAPMID:25181051
Fat4increases expressionISOFat4 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of FAT4 mRNAPMID:30816183 PMID:32528016 PMID:34947998
Fat4increases methylationISOFat4 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of FAT4 genePMID:28505145
Fat4multiple interactionsISOFat4 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with tributyltin] results in increased expression of FAT4 mRNAPMID:31129395
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