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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606557
Species: Homo sapiens
RGD Object: Gene
Symbol: ERCC6L
Name: ERCC excision repair 6 like, spindle assembly checkpoint helicase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ERCC6Ldecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ERCC6L mRNAPMID:29275510
ERCC6Lincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of ERCC6L genePMID:31601247
ERCC6Lmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of ERCC6L genePMID:31601247
ERCC6Laffects expressionISOErcc6l (Rattus norvegicus)6480464CTDbisphenol A affects the expression of ERCC6L mRNAPMID:25181051
ERCC6Ldecreases expressionISOErcc6l (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ERCC6L mRNAPMID:34947998
ERCC6Lincreases expressionISOErcc6l (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ERCC6L mRNAPMID:32145629
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