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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1591139
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eif4a3
Name: eukaryotic translation initiation factor 4A3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif4a3affects expressionEXP 6480464CTDbisphenol A affects the expression of EIF4A3 mRNAPMID:25181051
Eif4a3increases expressionEXP 6480464CTDbisphenol A results in increased expression of EIF4A3 mRNAPMID:34947998
Eif4a3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of EIF4A3 mRNAPMID:36041667
Eif4a3decreases expressionISOEIF4A3 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of EIF4A3 mRNAPMID:29275510
Eif4a3decreases methylationISOEIF4A3 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of EIF4A3 genePMID:31601247
Eif4a3multiple interactionsISOEIF4A3 (Homo sapiens)6480464CTD[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of EIF4A3 proteinPMID:31629898
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